Drug Metabolism Test (DMT)

SCILEX DMT can help physicians modify drug selection or dosage of certain prescribed opioids, tricyclic antidepressants (TCAs) selective serotonin re-uptake inhibitors (SSRIs) and serotonin norepinephrine re-uptake inhibitors (SNRIs). Through the analysis of an individuals DNA sequencing it can be determined if a patient is able to metabolize a specific drug normally, too fast, too slowly or not at all.  Taking the 'trial & error' out of prescribing high-risk medications profoundly improves patient safety, drug efficacy and reduces risk to the practice. 


Drug metabolism is a detoxification function the human body possesses to defend itself from environment hostility. Ideally, a drug should reach the site of action intact, cure the disease, and leave the body after it completes its mission. However, drug developers often face the dilemma that a potential drug is either metabolized/excreted from the body too fast, that the drug can not reach its therapeutic effect, or too slow, that it stays in the body for a long time, causing side effects.